Medical Device Development Solutions

Select examples of life science devices Techshot has developed

Vascular Grafts

Techshot has invented a process for manufacturing large human blood vessels using a patient’s own stem cells. Developed with $1.15 million in funding from two consecutive R&D contracts from the Pentagon’s Defense Health Program, the method produces vessels that are expected to initially benefit soldiers with severe injuries to their extremities. Soon after, they should to be available to anyone who, through trauma or disease, needs replacement arteries and/or veins.

Making strong implantable vascular grafts suitable for stitching, and sustaining potentially high arterial blood pressures, begins with a process called electrospinning. An electric field is applied to a thin liquid stream of natural and synthetic polymers, which are similar to materials used for biodegradable sutures. Like a spider spinning a web, the stream instantly solidifies into a very fine filament while being woven around a rotating mandrel, creating a tubular scaffold.

After stem cells collected from the patient’s own fat are printed on the tube, the finished graft is ready to be implanted. Upon complete healing in six to nine months, the polymer tube will have been absorbed by the body, leaving a natural blood vessel.

Nerve Stimulation

Electronic neuro-dermal blockade system for painless blood sampling/injections

CliniWave partnered with Techshot to develop CliniPulse, a medical device for neuro-dermal blockade, which is targeted at increasing compliance with finger stick blood glucose monitoring by eliminating the pain barrier to testing. It also may be useful for blood draws if further testing indicates that the area of anesthesia it induces can be increased and the electrode array is transparent, allowing vein identification.

Alternate approaches to blocking pain from the small skin breach in these procedures have limitations. Current approaches to reduce pain of skin breach by chemical means revolve around the application of local anesthetic cream. These creams take from 30 to 90 minutes to become effective. Side effects and limitations include significant time delay before full effect, prolonged action (hours), as well as potential local irritant and allergic effects. Local anesthetic infiltration is effective and swift, but again the prolonged action remains and it is a trade between one type of needle and another.

The electronic CliniPulse system quickly numbs the surface of the skin, permitting a painless breach. Moments after the event, full sensitivity is regained.

 

Cell Research (including stem cells)

  • Quadrupole Magnetic Sorter
  • Analytical Containment Transfer Tool (ACT2)
    • Transfers or stores fluid between or from experiment modules
  • ADvanced Space Experiment Processor (ADSEP)
    • High throughput processor of experiment cassettes
  • Cellcult
    • Dynamic cell culturing/tissue engineering cassette with a bioreactor
  • Flow Cytometer
    • Automated counter for blood, other cell types
  • Fluid Processing Cassette (FPC)
    • Custom configurable bags, pumps
  • Light Microscopy Module-Dynamic Stage (LMM-DS)
    • Microscope stage for observation of fluidics and suspensions
  • Multi-specimen Variable-gravity Platform (MVP)
    • 20 in-flight interchangeable specimen containers
    • Two 12.5” rotors, 0–2 g’s
    • Total environmental control
    • Video observation

Solutions for Protein Crystal Development & Research

  • ADvanced Space Experiment Processor (ADSEP)
    • Protein Crystal Growth Inserts
    • CRYMA

Bone Densitometry

  • Techshot Bone Densitometer

Rodent Research

  • Advanced Rodent Habitat
  • Bone Densitometer
  • Rodent Centrifuge

Colloids Research

Solutions for Colloids Research

  • Light Microscopy Module-Dynamic Stage                        
  • Colloids Specialty Cell

Avian Research (including embryology)

  • Avian Development Facility
  • Avian Hatchling Habitat

C. elegans Research

  • ADvanced Space Experiment Processor (ADSEP)
  • Fluid Processing Cassette

Plant Research

  • Multi-specimen Variable-gravity Platform (MVP)
    • 20 in-flight interchangeable specimen containers
    • Two 12.5” rotors, 0–2 g’s
    • Total environmental control
    • Video observation 

Drosophila Research

  • Multi-specimen Variable-gravity Platform (MVP)
    • 20 in-flight interchangeable specimen containers
    • Two 12.5” rotors, 0–2 g’s
    • Total environmental control
    • Video observation 

Other life and materials science research and/or processing needs

The images and descriptions of our equipment featured on this website are not intended to represent a finite take-it-or-leave-it catalog of available devices. 

Because research goals and science requirements vary from investigator to investigator, custom modifications to Techshot equipment and/or operational protocols are frequently made.  And when modifications aren’t enough, we can develop custom new devices and systems from the ground up that better meet your needs.

Techshot has a long history of developing the picks and shovels that research professionals use to make new discoveries. Just tell us what you’d like to do and we’ll help you make it happen.