Techshot has invented a process for manufacturing large human blood vessels using a patient’s own stem cells. Developed with $1.15 million in funding from two consecutive R&D contracts from the Pentagon’s Defense Health Program, the method produces vessels that are expected to initially benefit soldiers with severe injuries to their extremities. Soon after, they should be available to anyone who, through trauma or disease, needs replacement arteries and/or veins.
Making strong implantable vascular grafts suitable for stitching, and sustaining potentially high arterial blood pressures, begins with a process called electrospinning. An electric field is applied to a thin liquid stream of natural and synthetic polymers, which are similar to materials used for biodegradable sutures. Like a spider spinning a web, the stream instantly solidifies into a very fine filament while being woven around a rotating mandrel, creating a tubular scaffold.
After stem cells collected from the patient’s own fat are printed on the tube, the finished graft is ready to be implanted. Upon complete healing in six to nine months, the polymer tube will have been absorbed by the body, leaving a natural blood vessel.
The space flight-proven CELLCULT cassette contains a single 50-mL bioreactor with many options: rotation (or not) at a few RPM, perfusion, oxygenation and timed sampling.
This reactor system is suitable for cells of all types and aquatic organisms. It can also serve as a large-scale crystallization reactor or emulsion polymerization reactor. Any kind of aqueous suspension can be placed in the reactor vessel.
The images and descriptions of our equipment featured on this website are not intended to represent a finite take-it-or-leave-it catalog of available devices.
Because research goals and science requirements vary from investigator to investigator, custom modifications to Techshot equipment and/or operational protocols are frequently made. And when modifications aren’t enough, we can develop custom new devices and systems from the ground up that better meet your needs.
Techshot has a long history of developing the picks and shovels that research professionals use to make new discoveries. Just tell us what you’d like to do and we’ll help you make it happen.